team

Yanhong Shi, Ph.D, is Professor and Chair of Department of Neurodegenerative Diseases, and Director of Division of Stem Cell Biology Research at Beckman Research Institute of City of Hope. Dr. Shi is also the Herbert Horvitz Endowed Professor in Neuroscience, a beneficiary of the Christopher Family Endowed Innovation Fund for Alzheimer’s Disease Research in Honor of Vineta Christopher, and an elected fellow of the American Institute for Medical and Biological Engineering (AIMBE). The Shi lab at Beckman Research Institute of City of Hope is focused on human induced pluripotent stem cell (iPSC)-based disease modeling, drug discovery, and cell therapy development for debilitating diseases, including Alzheimer’s disease, Canavan disease, and cancer. The Shi lab has developed cGMP-compatible manufacturing processes for human iPSC derivation, differentiation, and genetic engineering, has demonstrated robust disease-modifying effects of human iPSC-derived cells as a cell therapy for Canavan disease in preclinical studies, and is rigorously developing human iPSC-based disease models and cell therapies for Alzheimer’s disease and cancer. Dr. Shi holds multiple patents on human iPSC-based technologies or cellular products and has published rigorously on human iPSC-related studies. Lab Website: https://www.cityofhope.org/yanhong-shi